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N3-1,4-cis-CHC-OH

N3-1,4-cis-CHC-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

[863222-21-3]

UNSPSC

12352211

Hazard Statement

H301-H372

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/n3-1-4-cis-chc-oh.html

Solubility

10 mM in DMSO

Smiles

OC([C@@H]1CC[C@@H](CC1)N=[N+]=[N-])=O

Molecular Formula

C7H11N3O2

Molecular Weight

169.18

Precautions

P260-P264-P270-P330-P405-P501

References & Citations

[1]Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14 (8) :779-789.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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