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2-Azido-adenosine

2-Azido-adenosine is a click chemistry reagent containing an azide group[1]. 2-Azido-adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

59587-07-4

UNSPSC

12352005

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2-azido-adenosine.html

Purity

99.59

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NC1=C2C(N([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C=N2)=NC(N=[N+]=[N-])=N1

Molecular Formula

C10H12N8O4

Molecular Weight

308.25

References & Citations

[1]Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14 (8) :779-789.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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