2-Azido-adenosine
2-Azido-adenosine is a click chemistry reagent containing an azide group[1]. 2-Azido-adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
[59587-07-4]
UNSPSC
12352005
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-azido-adenosine.html
Purity
99.59
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC1=C2C(N([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C=N2)=NC(N=[N+]=[N-])=N1
Molecular Formula
C10H12N8O4
Molecular Weight
308.25
References & Citations
[1]Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14 (8) :779-789.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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