N3-Gly-Aeg (Fmoc) -OH
N3-Gly-Aeg (Fmoc) -OH is a click chemistry reagent containing an azide group. PNA building-block that can be further modified using Click-chemistry[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
2606227-07-8
UNSPSC
12352005
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/n3-gly-aeg-fmoc-oh.html
Solubility
10 mM in DMSO
Smiles
[N-]=[N+]=NCC(N(CCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CC(O)=O)=O
Molecular Formula
C21H21N5O5
Molecular Weight
423.42
References & Citations
[1]Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14 (8) :779-789.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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