HadAB-IN-1
HadAB-IN-1 is a potent HadAB inhibitor. HadAB-IN-1 inhibits HadAB enzyme complexes activity with an IC50 value of 0.03 μM. HadAB-IN-1 also affects mycolic acid biosynthesis in Mycobacterium tuberculosis (Mtb) . HadAB-IN-1 can be used for the research of tuberculosis (TB) [1].
Product Specifications
CAS Number
1097120-47-2
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hadab-in-1.html
Solubility
10 mM in DMSO
Smiles
CS(=O)(NC(CCC1=CN(N=C1C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)Br)=O)=O
Molecular Formula
C19H17BrClN3O3S
Molecular Weight
482.78
References & Citations
[1]Vinayak Singh, et al. 1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in Mycobacterium tuberculosis. ACS Infect Dis. 2022 Nov 11;8 (11) :2315-2326.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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