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DAPOA (DCHA)

DAPOA DCHA is a click chemistry reagent containing an azide. DAPOA DCHA can be used in peptide synthesis as a linker that can be further modified at the azido-groups using Staudinger ligation or click-chemistry. This material can be used as a building block for dendrimeric structures[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Product Specifications

UNSPSC

12352211

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dapoa-dcha.html

Solubility

10 mM in DMSO

Smiles

[N-]=[N+]=NCC(CN=[N+]=[N-])OCC(O)=O.C1(CCCCC1)NC2CCCCC2

Molecular Formula

C17H31N7O3

Molecular Weight

381.47

References & Citations

[1]Meng G, et al. Modular click chemistry libraries for functional screens using a diazotizing reagent. Nature. 2019 Oct;574 (7776) :86-89.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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