DACN (Tos, Suc-OH)
DACN (Tos, Suc-OH) is a click chemistry reagent containing a cycloalkyne group. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. Such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes have served for reliable molecular conjugation in a broad range of fields. The nitrogens are used as connection points for a variety of functional units. DACNs possess high thermal and chemical stability along with comparable click reactivity[1].
Product Specifications
CAS Number
2109751-68-8
UNSPSC
12352005
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dacn-tos-suc-oh.html
Solubility
10 mM in DMSO
Smiles
O=C(CCC(N1CC#CCN(S(=O)(C2=CC=C(C)C=C2)=O)CCC1)=O)O
Molecular Formula
C18H22N2O5S
Molecular Weight
378.44
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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