(2R,4S) -H-D-Pro (4-N3) -OH
(2R,4S) -H-D-Pro (4-N3) -OH is a click chemistry reagent containing an azide group[1]. (2R,4S) -H-D-Pro (4-N3) -OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
[2137086-50-9]
UNSPSC
12352005
Hazard Statement
H301-H311-H331-H341
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2r-4s-h-d-pro-4-n3-oh.html
Solubility
10 mM in DMSO
Smiles
OC([C@H]1C[C@@H](CN1)N=[N+]=[N-])=O
Molecular Formula
C5H8N4O2
Molecular Weight
156.14
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P403+P233-P405-P501
References & Citations
[1]Takayama Y, Kusamori K, Nishikawa M. Click Chemistry as a Tool for Cell Engineering and Drug Delivery. Molecules. 2019 Jan 4;24 (1) :172.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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