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Mal-AMCHC-N-Propargylamide

Mal-AMCHC-N-Propargylamide is a click chemistry reagent containing an azide group. Mal-AMCHC-N-Propargylamide can be a bio-conjugation reagent for antibody-agent-conjugate synthesis using Click-Chemistry[1].

Product Specifications

CAS Number

2027476-42-0

UNSPSC

12352005

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/mal-amchc-n-propargylamide.html

Solubility

10 mM in DMSO

Smiles

O=C(C=CC1=O)N1C[C@@H]2CC[C@H](CC2)C(NCC#C)=O

Molecular Formula

C15H18N2O3

Molecular Weight

274.32

References & Citations

[1]Moon SJ, et, al. Antibody conjugates of 7-ethyl-10-hydroxycamptothecin (SN-38) for targeted cancer chemotherapy. J Med Chem. 2008 Nov 13;51 (21) :6916-26.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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