N3-TFBA-O2Oc
N3-TFBA-O2Oc is a click chemistry reagent containing an azide group and an aryl group. Aryl azides are well-known precursors of nitrenes and have been introduced by Fleet et al. as versatile photoaffinity labeling agents to probe biological receptors. This type of compounds has been used as photo-cross linker (λmax=258 nm) in estrogen receptor studies and for direct surface coating of carbon and organic based polymers[1][2][3]. N3-TFBA-O2Oc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
[1993119-45-1]
UNSPSC
12352005
Hazard Statement
H228
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/n3-tfba-o2oc.html
Solubility
10 mM in DMSO
Smiles
[N-]=[N+]=NC1=C(C(F)=C(C(F)=C1F)C(NCCOCCOCC(O)=O)=O)F
Molecular Formula
C13H12F4N4O5
Molecular Weight
380.25
Precautions
H228
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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