(2R,3S) -Fmoc-Abu (3-N3) -OH

(2R,3S) -Fmoc-Abu (3-N3) -OH is a click chemistry reagent containing an azide group[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

[1932349-21-7]

UNSPSC

12352005

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2r-3s-fmoc-abu-3-n3-oh.html

Solubility

10 mM in DMSO

Smiles

[N-]=[N+]=N[C@@H](C)[C@H](C(O)=O)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O

Molecular Formula

C19H18N4O4

Molecular Weight

366.37

References & Citations

[1]Al Ayed K, et al. Synthetic studies with the brevicidine and laterocidine lipopeptide antibiotics including analogues with enhanced properties and in vivo efficacy. Chem Sci. 2022 Feb 23;13 (12) :3563-3570.