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CalFluor 488 Azide

CalFluor 488 Azide is a water-soluble fluorogenic azide probe. CalFluor 488 Azide is activated by Cu-catalyzed or metal-free click reaction. CalFluor 488 Azide is not fluorescent until it is reacted with alkynes[1][2]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

1798305-98-2

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/calfluor-488-azide.html

Purity

97.85

Solubility

H2O

Smiles

[N-]=[N+]=NC1=CC(C2=C3C=CC(C=C3OC4=C2C=CC(O)=C4)=O)=C(C=C1OCCOCC[N+](C)(CCCS(=O)([O-])=O)C)OCCOCC[N+](C)(CCCS(=O)([O-])=O)C

Molecular Formula

C37H49N5O13S2

Molecular Weight

835.94

References & Citations

[1]Neugebauer ME, et al. Reaction pathway engineering converts a radical hydroxylase into a halogenase. Nat Chem Biol. 2022 Feb;18 (2) :171-179.|[2]Hu J, et al. Chiral lipid bilayers are enantioselectively permeable. Nat Chem. 2021 Aug;13 (8) :786-791.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Frequently Asked Questions

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