Boc-D-Lys (N3) -OH
Boc-D-Lys (N3) -OH is a Boc-protected amino acid derivative, can be used as a click chemistry reagent and an intermediate for synthesis of linkers[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
[1620410-04-9]
UNSPSC
12352211
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/boc-d-lys-n3-oh.html
Solubility
10 mM in DMSO
Smiles
CC(C)(C)OC(N[C@@H](C(O)=O)CCCCN=[N+]=[N-])=O
Molecular Formula
C11H20N4O4
Molecular Weight
272.30
References & Citations
[1]Sandrine Gerber, et al. Compounds for functionalizing biomaterials. WO2014111545
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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CYP21B (Cytochrome P450 21B, CYP21A2, CPS1, CA21H, CAH1, CYP21, CYP21-B, 21-OHase, Steroid 21-hydroxylase, Cytochrome P450, Family 21, Subfamily A, Polypeptide 2)
