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H-L-Orn (N3) -OH (hydrochloride)

H-L-Orn (N3) -OH (hydrochloride) is a click chemistry reagent containing an azide group. H-L-Orn (N3) -OH (hydrochloride) can be used for the research of various biochemical[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

[1782935-10-7]

UNSPSC

12352211

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/h-l-orn-n3-oh-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

[N-]=[N+]=NCCC[C@H](N)C(O)=O.Cl

Molecular Formula

C5H11ClN4O2

Molecular Weight

194.62

References & Citations

[1]Ye Wu, et al. A novel peptide stapling strategy enables the retention of ring-closing amino acid side chains for the Wnt/β-catenin signalling pathway. Chem Sci. 2017 Nov 1;8 (11) :7368-7373.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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