Fmoc-L-Tyr (2-azidoethyl) -OH

Fmoc-L-Tyr (2-azidoethyl) -OH is a click chemistry reagent containing an azide group. Fmoc-L-Tyr (2-azidoethyl) -OH is unnatural Fmoc-protected Tyrosine derivative bears an azidoethyl substitution as reactive handle e.g. for biorthogonal conjugations, via a Cu (I) -catalyzed 1,3-dipolar Click cycloaddition with alkynes. And azido-UAAs can be employed as IR reporters[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.