Fmoc-L-Lys (4-N3-Z) -OH
Fmoc-L-Lys (4-N3-Z) -OH is a click chemistry reagent containing an azide group. Fmoc-L-Lys (4-N3-Z) -OH acts as Lysine building-block for SPPS containing an Azide moiety as a bioorthogonal ligation handle, an infrared probe and a photo-affinity reagent. It can be decaged by trans-cyclooctenols via a strain-promoted 1,3-dipolar cycloaddition[1][2]. Fmoc-L-Lys (4-N3-Z) -OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
1446511-14-3
UNSPSC
12352005
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/fmoc-l-lys-4-n3-z-oh.html
Solubility
10 mM in DMSO
Smiles
O=C(O)[C@H](CCCCNC(OCC1=CC=C(N=[N+]=[N-])C=C1)=O)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O
Molecular Formula
C29H29N5O6
Molecular Weight
543.57
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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