Boc-L-Tyr (2-azidoethyl) -OH
Boc-L-Tyr (2-azidoethyl) -OH (N-Boc-O- (2-azidoethyl) -L-tyrosine) is a click chemistry reagent containing an azide group[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
1434445-10-9
Product Name Alternative
N-Boc-O- (2-azidoethyl) -L-tyrosine
UNSPSC
12352005
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/boc-l-tyr-2-azidoethyl-oh.html
Solubility
10 mM in DMSO
Smiles
CC(C)(C)OC(N[C@H](C(O)=O)CC1=CC=C(C=C1)OCCN=[N+]=[N-])=O
Molecular Formula
C16H22N4O5
Molecular Weight
350.37
References & Citations
[1]Xin BT, et, al. Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits. J Med Chem. 2019 Feb 14;62 (3) :1626-1642.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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