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Fmoc-L-MeLys (N3) -OH

Fmoc-L-MeLys (N3) -OH is a click chemistry reagent containing an azide. Fmoc-L-MeLys (N3) -OH is a SPPS building-block for the introduction of N-Me-Lys that can be modified at the N3-group using Click-chemistry[1]. Fmoc-L-MeLys (N3) -OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

1263721-14-7

UNSPSC

12352005

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/fmoc-l-melys-n3-oh.html

Solubility

10 mM in DMSO

Smiles

[N-]=[N+]=NCCCC[C@@H](C(O)=O)N(C)C(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O

Molecular Formula

C22H24N4O4

Molecular Weight

408.45

References & Citations

[1]Doi T, et al. Solid-phase total synthesis of (-) -apratoxin A and its analogues and their biological evaluation. Chem Asian J. 2011 Jan 3;6 (1) :180-8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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