Z-L-Aha-OH (DCHA)
Z-L-Aha-OH (DCHA) is a click chemistry reagent containing azide group[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
[1423018-09-0]
UNSPSC
12352005
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/z-l-aha-oh-dcha.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC1=CC=CC=C1)N[C@H](C(O)=O)CCN=[N+]=[N-].C2(CCCCC2)NC3CCCCC3
Molecular Formula
C24H37N5O4
Molecular Weight
459.58
References & Citations
[1]Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14 (8) :779-789.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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