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Fmoc-L-Lys (N3-Gly) -OH

Fmoc-L-Lys (N3-Gly) -OH is a click chemistry reagent containing a lysine-containing azidoacetyl group building-block for SPPS and can be used for various biochemical studies[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

1198617-89-8

UNSPSC

12352005

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/fmoc-l-lys-n3-gly-oh.html

Solubility

10 mM in DMSO

Smiles

[N-]=[N+]=NCC(NCCCC[C@@H](C(O)=O)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)=O

Molecular Formula

C23H25N5O5

Molecular Weight

451.48

References & Citations

[1]Yusuke Fujiwara, et al. Live-cell epigenome manipulation by synthetic histone acetylation catalyst system. Proc Natl Acad Sci U S A. 2021 Jan 26;118 (4) :e2019554118.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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