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Icotinib-d4

Product Specifications

UNSPSC Description

Icotinib-d4 is the deuterium-labeled Icotinib (HY-15164A). Icotinib-d4 (BPI-2009) is a potent and specific EGFR inhibitor with an IC50 of 5 nM; also inhibits mutant EGFRL858R, EGFRL858R/T790M, EGFRT790M and EGFRL861Q. Icotinib-d4 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Target Antigen

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Field of Research

Others

Solubility

10 mM in DMSO

Smiles

[2H]C1([2H])C([2H])([2H])OCCOC2=CC(C(NC3=CC(C#C)=CC=C3)=NC=N4)=C4C=C2OCCO1

Molecular Weight

395.44

Shipping Conditions

Room temperature

Clinical Information

No Development Reported

CAS Number

1567366-82-8

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