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Alkyne-SNAP

Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation[1].

Product Specifications

CAS Number

1104822-07-2

UNSPSC

12352005

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/alkyne-snap.html

Purity

99.32

Solubility

10 mM in DMSO

Smiles

O=C(CCC#C)NCC1=CC=C(COC2=NC(N)=NC3=C2NC=N3)C=C1

Molecular Formula

C18H18N6O2

Molecular Weight

350.37

References & Citations

[1]Broichhagen J, et al. Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand. ACS Cent Sci. 2015 Oct 28;1 (7) :383-93.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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