PI3K/VEGFR2-IN-1
Product Specifications
UNSPSC Description
PI3K/VEGFR2-IN-1 is a potent dual PI3K/VEGFR2 inhibitor with IC50 values of 2.21 and 68 μM for PI3K and VEGFR2, respectively. PI3K/VEGFR2-IN-1 induces apoptosis. PI3K/VEGFR2-IN-1 can be used in research of cancer[1].
Target Antigen
Apoptosis; PI3K; VEGFR
Type
Reference compound
Related Pathways
Apoptosis;PI3K/Akt/mTOR;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3k-vegfr2-in-1.html
Solubility
10 mM in DMSO
Smiles
S=C(N/N=C(C1=CC2=CC=CC=C2O1)\C)NC3=CC=C(Cl)C=C3
Molecular Weight
343.83
References & Citations
[1]El-Khouly OA, et, al. Design, synthesis and computational study of new benzofuran hybrids as dual PI3K/VEGFR2 inhibitors targeting cancer. Sci Rep. 2022 Oct 12;12(1):17104.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151635/PI3K-VEGFR2-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151635/
Clinical Information
No Development Reported
CAS Number
2851067-08-6
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