HCAIX-IN-14
HCAIX-IN-14 (compound 5a) is a potent inhibitor of human CA IX with a Ki value of 134.8 nM[1].
Product Specifications
CAS Number
77113-78-1
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hcaix-in-14.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(N2C(C)(C)N=C(N)N=C2N)C=C1)(N)=O.Cl
Molecular Formula
C11H17ClN6O2S
Molecular Weight
332.81
References & Citations
[1]Zain-Alabdeen AI, et al. Synthesis and anticancer activity of new benzensulfonamides incorporating s-triazines as cyclic linkers for inhibition of carbonic anhydrase IX. Sci Rep. 2022 Oct 6;12 (1) :16756.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA IX
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