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11β-HSD1-IN-11

11β-HSD1-IN-11 (Compound c1a) is a competitive 11β-HSD1 inhibitor with IC50s of 0.34 μM and 0.13 μM against rat and human 11β-HSD1, respectively[1].

Product Specifications

CAS Number

859721-81-6

UNSPSC

12352005

Target

11β-HSD

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/11β-hsd1-in-11.html

Solubility

10 mM in DMSO

Smiles

FC(C1=CC=C(C(CS(=O)(C2=CC=CC=C2)=O)=O)C=C1)(F)F

Molecular Formula

C15H11F3O3S

Molecular Weight

328.31

References & Citations

[1]Naredo-Gonzalez G, et al. Non-invasive in vivo assessment of 11β-hydroxysteroid dehydrogenase type 1 activity by 19F-Magnetic Resonance Spectroscopy. Sci Rep. 2022 Sep 29;12 (1) :16268.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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