11β-HSD1-IN-11
11β-HSD1-IN-11 (Compound c1a) is a competitive 11β-HSD1 inhibitor with IC50s of 0.34 μM and 0.13 μM against rat and human 11β-HSD1, respectively[1].
Product Specifications
CAS Number
859721-81-6
UNSPSC
12352005
Target
11β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/11β-hsd1-in-11.html
Solubility
10 mM in DMSO
Smiles
FC(C1=CC=C(C(CS(=O)(C2=CC=CC=C2)=O)=O)C=C1)(F)F
Molecular Formula
C15H11F3O3S
Molecular Weight
328.31
References & Citations
[1]Naredo-Gonzalez G, et al. Non-invasive in vivo assessment of 11β-hydroxysteroid dehydrogenase type 1 activity by 19F-Magnetic Resonance Spectroscopy. Sci Rep. 2022 Sep 29;12 (1) :16268.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TP723914 100 µg
SARS-CoV-2 Spike S1 Recombinant Protein with hFc and His tag
Sign In for Pricing
View Details