PARP-2-IN-2
Product Specifications
UNSPSC Description
PARP-2-IN-2 (compound 27) is a PARP?2 inhibitor with an IC50 value of 0.057 μM. PARP-2-IN-2 induces cell cycle arrest and apoptosis of MCF-7 breast cancer cells. PARP-2-IN-2 can be used for the research of cancer[1].
Target Antigen
Apoptosis; PARP
Type
Reference compound
Related Pathways
Apoptosis;Cell Cycle/DNA Damage;Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/parp-2-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(C2=NC3=CC(Cl)=CC=C3O2)C=C1)CCN(CC)CC
Molecular Weight
371.86
References & Citations
[1]El-Ghobashy NM, et al. Synthesis, biological evaluation, and molecular modeling studies of new benzoxazole derivatives as PARP-2 inhibitors targeting breast cancer. Sci Rep. 2022 Sep 28;12(1):16246.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151624/PARP-2-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151624/
Clinical Information
No Development Reported
CAS Number
2915651-00-0
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