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SEH inhibitor-13

SEH inhibitor-13 (compound 43) is a potent soluble epoxide hydrolase (sEH) inhibitor, with an IC50 of 0.4 μM[1].

Product Specifications

UNSPSC

12352005

Target

Epoxide Hydrolase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/seh-inhibitor-13.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC(N=C(SCC2=CC=CC=C2OC(F)(F)F)N3)=C(C=C1)C3=O)NCC(C)(C)C

Molecular Formula

C22H22F3N3O3S

Molecular Weight

465.49

References & Citations

[1]Turanlı S, et al. Quinazoline-4 (3H) -one-7-carboxamide Derivatives as Human Soluble Epoxide Hydrolase Inhibitors with Developable 5-Lipoxygenase Activating Protein Inhibition. ACS Omega. 2022 Oct 5;7 (41) :36354-36365.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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