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UAMC-00050

UAMC-00050 is a potent trypsin-like serine protease inhibitor. UAMC-00050 can be used in research of dry eye syndrome and ocular inflammation[1].

Product Specifications

CAS Number

2842774-51-8

UNSPSC

12352005

Target

Ser/Thr Protease

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/uamc-00050.html

Solubility

10 mM in DMSO

Smiles

O=P(C(NC(OCC1=CC=CC=C1)=O)CC2=CC=C(C=C2)NC(N)=N)(OC3=CC=C(C=C3)NC(C)=O)OC4=CC=C(C=C4)NC(C)=O.Cl

Molecular Formula

C33H36ClN6O7P

Molecular Weight

695.10

References & Citations

[1]Ceradini D, et, al. Improved synthesis of the selected serine protease uPA inhibitor UAMC-00050, a lead compound for the treatment of dry eye disease. 2022 Sep 30;26 (10) :2937-46.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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