PARP7-IN-12
PARP7-IN-12 is a potent PARP7 Inhibitor with an IC50 value of 7.836 nM. PARP7-IN-12 can be used in research of cancer[1].
Product Specifications
CAS Number
2819700-92-8
UNSPSC
12352005
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/parp7-in-12.html
Solubility
10 mM in DMSO
Smiles
CC1=C2C(N3[C@@](CCO2)([H])CN(CC3)C(CCOC[C@H](C)OC4=C(C(NN=C4)=O)C(F)(F)F)=O)=NC=C1Cl
Molecular Formula
C23H27ClF3N5O5
Molecular Weight
545.94
References & Citations
[1]Jun LH, et, al. Tricyclic derivatives useful as parp7 inhibitors. WO2022170974.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PARP7
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