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EGFR/CDK2-IN-1

EGFR/CDK2-IN-1 (Compound 3b) is an EGFR/CDK2 inhibitor. EGFR/CDK2-IN-1 shows good cytotoxicity against MCF7 and HepG2 cells. EGFR/CDK2-IN-1 can be used in cancer research[1].

Product Specifications

CAS Number

2841405-96-5

UNSPSC

12352005

Target

CDK; EGFR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/egfr-cdk2-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C(Br)C=C1)/C=C/C2=CC=C(C3=CC=CC=C3Cl)O2

Molecular Formula

C19H12BrClO2

Molecular Weight

387.65

References & Citations

[1]Altowyan MS, et al. Synthesis, Characterization, and Cytotoxicity of New Spirooxindoles Engrafted Furan Structural Motif as a Potential Anticancer Agent. ACS Omega. 2022 Sep 27;7 (40) :35743-35754.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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