Mtb-cyt-bd oxidase-IN-6
Mtb-cyt-bd oxidase-IN-6 is a potent Mycobacterium tuberculosis (Mtb) cytochrome bd (cyt-bd) oxidase (MtbCyt-bd Oxidase) inhibitor with an IC50 value of 0.35 μM. Mtb-cyt-bd oxidase-IN-6 can effectively inhibit the growth of Mtb (MIC= 4 μM) . Mtb-cyt-bd oxidase-IN-6 can be used in the study of tuberculosis[1].
Product Specifications
CAS Number
1246461-10-8
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mtb-cyt-bd-oxidase-in-6.html
Solubility
10 mM in DMSO
Smiles
O=C1C(CC[C@H](C)CC/C=C(C)\C)=C(C)NC2=C1C=CC=C2
Molecular Formula
C20H27NO
Molecular Weight
297.43
References & Citations
[1]Lawer A, et, al. Synthesis and Biological Evaluation of Aurachin D Analogues as Inhibitors of Mycobacterium tuberculosis Cytochrome bd Oxidase. ACS Med Chem Lett. 2022 Sep 26;13 (10) :1663-1669.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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