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Mtb-cyt-bd oxidase-IN-4

Mtb-cyt-bd oxidase-IN-4 (compound 1g) is a Mycobacterium tuberculosis cytochrome bd oxidase (Mtb cyt-bd oxidase) inhibitor with an IC50 value of 0.25 μM. Mtb-cyt-bd oxidase-IN-4 inhibits the growth of Mycobacterium tuberculosis (MIC=8 μM) . Mtb-cyt-bd oxidase-IN-4 can be used in tuberculosis research[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/mtb-cyt-bd-oxidase-in-4.html

Solubility

10 mM in DMSO

Smiles

C/C(C)=C\CC/C(C)=C/CC/C(C)=C/CC1=C(NC2=CC=C(F)C=C2C1=O)C

Molecular Formula

C25H32FNO

Molecular Weight

381.53

References & Citations

[1]Lawer A, et al. Synthesis and Biological Evaluation of Aurachin D Analogues as Inhibitors of Mycobacterium tuberculosis Cytochrome bd Oxidase. ACS Med Chem Lett. 2022 Sep 26;13 (10) :1663-1669.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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