Mtb-cyt-bd oxidase-IN-3
Mtb-cyt-bd oxidase-IN-3 (compound 1u) is a Mycobacterium tuberculosis cytochrome bd oxidase (Mtb cyt-bd oxidase) inhibitor with an IC50 value of 0.36 μM. Mtb-cyt-bd oxidase-IN-3 inhibits the growth of Mycobacterium tuberculosis (MIC=32 μM) . Mtb-cyt-bd oxidase-IN-3 can be used in tuberculosis research[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mtb-cyt-bd-oxidase-in-3.html
Solubility
10 mM in DMSO
Smiles
COC1=C2C(C(C/C=C(CC/C=C(CC/C=C(C)\C)\C)\C)=C(NC2=CC=C1)C)=O
Molecular Formula
C26H35NO2
Molecular Weight
393.56
References & Citations
[1]Lawer A, et al. Synthesis and Biological Evaluation of Aurachin D Analogues as Inhibitors of Mycobacterium tuberculosis Cytochrome bd Oxidase. ACS Med Chem Lett. 2022 Sep 26;13 (10) :1663-1669.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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