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PNE-Lyso

Product Specifications

UNSPSC Description

PNE-Lyso is a activatable fluorescent probe. PNE-Lyso can be used to detect intracellular pH and hexosaminidases with two kinds of fluorescence signals. PNE-Lyso can be used to distinguish apoptosis from necrosis through visualizing lysosome morphology. PNE-Lyso is capable of investigating the agent-induced cell death process[1].

Target Antigen

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pne-lyso.html

Solubility

10 mM in DMSO

Smiles

OCC1OC(OC2=CC3=C(C=C4C(O3)=C(CCC4)/C=C/C5=CC=NC=C5)C=C2)C(NC(C)=O)C(O)C1O

Molecular Weight

506.55

References & Citations

[1]Wang Y, et al. Discrimination of Cell Death Types with an Activatable Fluorescent Probe through Visualizing the Lysosome Morphology. Anal Chem. 2022 Oct 4;94(39):13413-13421.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-151544/PNE-Lyso-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-151544/

Clinical Information

No Development Reported

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