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PBRM1-BD2-IN-3

PBRM1-BD2-IN-3 (compound 12) is a potent PBRM1-BD2 inhibitor with an IC50 value of 1.1 μM. PBRM1-BD2 Inhibitor can be used to research anticancer[1].

Product Specifications

CAS Number

2819989-58-5

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pbrm1-bd2-in-3.html

Solubility

10 mM in DMSO

Smiles

O=C1NC(C2=CC=CC=C2)NC3=C1C(Cl)=CC=C3

Molecular Formula

C14H11ClN2O

Molecular Weight

258.70

References & Citations

[1]Shishodia S, et al. Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening. J Med Chem. 2022 Oct 13.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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