Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

PBRM1-BD2-IN-2

PBRM1-BD2-IN-2 is a selective and cell-active polybromo-1 (PBRM1) bromodomain inhibitor. PBRM1-BD2-IN-2 has binding affinity and inhibitory activity for PBRM1-BD2 with Kd and IC50 values of 9.3 μM and 1.0 μM, respectively. PBRM1-BD2-IN-2 can be used for the research of cancer[1].

Product Specifications

CAS Number

2819989-57-4

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pbrm1-bd2-in-2.html

Purity

99.0

Solubility

DMSO : 45 mg/mL (ultrasonic; warming)

Smiles

O=C1NC(C2=C(F)C=CC=C2Cl)NC3=C1C(Cl)=CC=C3

Molecular Formula

C14H9Cl2FN2O

Molecular Weight

311.14

References & Citations

[1]Shifali Shishodia, et al. Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening. J Med Chem. 2022 Oct 13.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

MKP-4 (D-3) : m-IgGκ BP-HRP Bundle
sc-521392 1 Kit

MKP-4 (D-3) : m-IgGκ BP-HRP Bundle

Sign In for Pricing
View Details
HSP90AB1, CT (HSP90AB1, HSP90B, HSPC2, HSPCB, Heat shock protein HSP 90-beta, Heat shock 84kD) (MaxLight 490) discontinued
036794-ML490 100 µL

HSP90AB1, CT (HSP90AB1, HSP90B, HSPC2, HSPCB, Heat shock protein HSP 90-beta, Heat shock 84kD) (MaxLight 490) discontinued

Sign In for Pricing
View Details
GPR177 sgRNA CRISPR Lentivector (Human) (Target 3)
K0900004 1.0 µg DNA

GPR177 sgRNA CRISPR Lentivector (Human) (Target 3)

Sign In for Pricing
View Details
CASR
MBS8562501-01 0.2 mL

CASR

Sign In for Pricing
View Details
CASR
MBS8562501-02 0.1 mL (AF405L)

CASR

Sign In for Pricing
View Details
CASR
MBS8562501-03 0.1 mL (AF405S)

CASR

Sign In for Pricing
View Details