SIRT2-IN-10
SIRT2-IN-10 (Compound 12) is a potent SIRT2 inhibitor with an IC50 of 1.3 μM. SIRT2-IN-10 can be used for the research of cancer and neurodegenerative disease[1].
Product Specifications
CAS Number
296793-09-4
UNSPSC
12352005
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sirt2-in-10.html
Solubility
10 mM in DMSO
Smiles
O=C(CSC1=NC2=C(C(C=CC=C3)=C3N2CC4=CC=CC=C4)N=N1)NC5=C(C=CC=C6)C6=CC=C5
Molecular Formula
C28H21N5OS
Molecular Weight
475.56
References & Citations
[1]Shengyong Yang, et al. The purposes of 5H- [1,2,4] triazine [5,6-b] indole derivatives of 3 substitutions. Patent CN108309982A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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