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Diamino lipid DAL4

Diamino lipid DAL4 is diamino lipid for the preparation of lipid nanoparticles (LNPs) encapsulated with mRNAs encoding cytokines including IL-12, IL-27 and GM-CSF. Diamino lipid DAL4 delivers mRNA to tumor cells to exert anti-tumor activity[1].

Product Specifications

CAS Number

2939000-43-6

UNSPSC

12352200

Target

Liposome

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/diamino-lipid-dal4.html

Solubility

10 mM in DMSO

Smiles

CCCCCCCCCCCCN(CCCN(CCCCCC(NCC1=C(B(O)O)C=C(F)C=C1)=O)CCCCCCCCCCCC)CCCCCCCCCCCC

Molecular Formula

C52H99BFN3O3

Molecular Weight

844.17

References & Citations

[1]Liu JQ, et al. Intratumoral delivery of IL-12 and IL-27 mRNA using lipid nanoparticles for cancer immunotherapy. J Control Release. 2022 May;345:306-313.

Shipping Conditions

Room temperature

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Frequently Asked Questions

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