PXS-6302
PXS-6302 is an irreversible lysyl oxidase inhibitor with IC50s of 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4), respectively. PXS-6302 has readily skin penetrability, reduces collagen deposition and significantly improves scar appearance[1].
Product Specifications
CAS Number
2584947-54-4
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pxs-6302.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC/C=C(C(F)(S(=O)(C1=CC=CC=C1)=O)F)\F
Molecular Formula
C10H10F3NO2S
Molecular Weight
265.25
References & Citations
[1]Chaudhari N, et al. Topical application of an irreversible small molecule inhibitor of lysyl oxidases ameliorates skin scarring and fibrosis. Nat Commun. 2022 Sep 22;13 (1) :5555.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNUM1175-50 1x 50 µL
PTH / Parathyroid Hormone (N-Terminal) (PTH/1175), 1mg/mL
Sign In for Pricing
View Details 
BNC742076-100 1x 100 µL
GFAP (Astrocyte & Neural Stem Cell Marker) (GFAP/2076), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC882622-500 1x 500 µL
MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNCB1129-500 1x 500 µL
MHC II (HLA-DP) (beta chain) (Bra-14), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
TRC-D448110-250MG 250 mg
2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-3-bromopropan-2-ol
Sign In for Pricing
View Details