CAII-IN-3
CAII-IN-3 (compound 3h), a thiosemicarbazones derivatives, is a potent carbonic anhydrase-II (CA-II) inhibitor with an IC50 value of 13.4 µM[1].
Product Specifications
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/caii-in-3.html
Solubility
10 mM in DMSO
Smiles
FC1=CC(F)=CC=C1NC(N/N=C/C=C/C2=CC=C(C=C2)N(C)C)=S
Molecular Formula
C18H18F2N4S
Molecular Weight
360.42
References & Citations
[1]Rasool A, et al. Bis-pharmacophore of cinnamaldehyde-clubbed thiosemicarbazones as potent carbonic anhydrase-II inhibitors. Sci Rep. 2022 Sep 27;12 (1) :16095.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA II
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