CAII-IN-1
CAII-IN-1 (compound 3n), a thiosemicarbazide derivative, is a potent, selective carbonic anhydrase-II (CA-II) inhibitor with an IC50 value of 10.3 μM for bovine CA-II. CAII-IN-1 can be used in research of carbonic anhydrase related biological disorders[1].
Product Specifications
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/caii-in-1.html
Solubility
10 mM in DMSO
Smiles
CN(C1=CC=C(C=C1)/C=C/C=N/NC(NCC2=CC=C(C=C2)F)=S)C
Molecular Formula
C19H21FN4S
Molecular Weight
356.46
References & Citations
[1]Rasool A, et, al. Bis-pharmacophore of cinnamaldehyde-clubbed thiosemicarbazones as potent carbonic anhydrase-II inhibitors. Sci Rep. 2022 Sep 27;12 (1) :16095.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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