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CypD-IN-4

Product Specifications

UNSPSC Description

CypD-IN-4 is a potent and subtype-selective cyclophilin D (CypD) inhibitor. CypD-IN-4 has CypD affinity with an IC50 value of 0.057 μM. CypD-IN-4 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy and diabetes[1].

Target Antigen

Cyclophilin

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cypd-in-4.html

Solubility

10 mM in DMSO

Smiles

NCCOCCNC([C@@H]1CCNC(/C=C/C(N2CCC[C@](C2)(C(N[C@H](C(NCC3=C(CC(N1)=O)C=CC=C3)=O)CC4=CC=C(C=C4)C5=CC=C(C=C5)C(CC(O)=O)CC(O)=O)=O)CC6=CC=CC=C6)=O)=O)=O

Molecular Weight

986.12

References & Citations

[1]Alexander A Peterson, et al. Discovery and molecular basis of subtype-selective cyclophilin inhibitors. Nat Chem Biol. 2022 Sep 26.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-151488/CypD-IN-4-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-151488/

Clinical Information

No Development Reported

CAS Number

3023438-19-6

Curated Selection

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