GLUT1-IN-1
GLUT1-IN-1 is a glucose transporter 1 (GLUT1) inhibitor and has a GLUT1-specific inactivation ability. GLUT1-IN-1 exhibits concentration-dependent cytotoxicity for HeLa, A549 and HepG2 cells with IC50 values of 5.49 μM, 11.14 μM, and 8.73 μM, respectively. GLUT1-IN-1 can be used for the research of photodynamic therapy (PDT) and severals cancer[1].
Product Specifications
UNSPSC
12352005
Target
GLUT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/glut1-in-1.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)OCCN2N=NC(CNC(CCC3=[N]4C(C=C3I)=CC5=C(C(I)=C(N5B4(F)F)C)C)=O)=C2)O)O)O
Molecular Formula
C25H31BF2I2N6O7
Molecular Weight
830.17
References & Citations
[1]Kazuki Miura, et al. Photodynamic Therapy by Glucose Transporter 1-Selective Light Inactivation. ACS Omega Article ASAP.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GLUT1
Frequently Asked Questions
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