GID4 Ligand 3
GID4 Ligand 3 (compound 16) is a binder of GID4 with an Kd value of 110 μM in vitro and an IC50 value of 148.5 μM. GID4 Ligand 3 can be used for the research related to cereblon and Von Hippel-Lindau[1].
Product Specifications
CAS Number
[340007-39-8]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gid4-ligand-3.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=CC(NC2=NCC(C)S2)=C1
Molecular Formula
C10H12N2OS
Molecular Weight
208.28
References & Citations
[1]Chana CK, et al. Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4. J Med Chem. 2022 Sep 18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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