SARS-CoV-2-IN-33

SARS-CoV-2-IN-33 (compound 3m) is a COVID-19 inhibitor. SARS-CoV-2-IN-33 shows anti-proliferative activity against cancer cells. SARS-CoV-2-IN-33 exhibits comparatively good binding affinity (-8.0 Kcal/mole) to COVID-19 main protease (Mpro) (PDB ID: 6LU7) . SARS-CoV-2-IN-33 can be used in studies of cancer and COVID-19[1].

Product Specifications

CAS Number

[299919-79-2]

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/sars-cov-2-in-33.html

Solubility

10 mM in DMSO

Smiles

OC1=C(C(C2=C(N(C3=CC=CC=C3)N=C2C)O)C4=CC(OC)=C(C(OC)=C4)OC)C(C)=NN1C5=CC=CC=C5

Molecular Formula

C30H30N4O5

Molecular Weight

526.58

References & Citations

[1]Gupta A, et al. Visible Light-Promoted Green and Sustainable Approach for One-Pot Synthesis of 4, 4’- (Arylmethylene) bis (1H-pyrazol-5-ols), In Vitro Anticancer Activity, and Molecular Docking with Covid-19 Mpro. ACS Omega, 2022.