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GID4 Ligand 2

GID4 Ligand 2 (compound 67) is a selective GID4 binder (IC50=18.9 μM; Kd=17 μM) . GID4 Ligand 2 can be used for the synthesis of PROTACs[1].

Product Specifications

CAS Number

[3031442-90-4]

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gid4-ligand-2.html

Solubility

10 mM in DMSO

Smiles

NC1=CC=CC2=C1CCNC2C3=CC=CC=C3

Molecular Formula

C15H16N2

Molecular Weight

224.30

References & Citations

[1]Chana CK, et al. Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4. J Med Chem. 2022 Sep 18.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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