GID4 Ligand 2
GID4 Ligand 2 (compound 67) is a selective GID4 binder (IC50=18.9 μM; Kd=17 μM) . GID4 Ligand 2 can be used for the synthesis of PROTACs[1].
Product Specifications
CAS Number
[3031442-90-4]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gid4-ligand-2.html
Solubility
10 mM in DMSO
Smiles
NC1=CC=CC2=C1CCNC2C3=CC=CC=C3
Molecular Formula
C15H16N2
Molecular Weight
224.30
References & Citations
[1]Chana CK, et al. Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4. J Med Chem. 2022 Sep 18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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