ZIKV-IN-3
ZIKV-IN-3 (compound 5a), an andrographolide derivatives, is a potent ZIKV NS5 methyl transferase (MTase) inhibitor with an IC50 value of 18.34 μM. ZIKV-IN-3 inhibits ZIKV replication and infection. ZIKV-IN-3 can be used in research of Zika virus (ZIKV) [1].
Product Specifications
CAS Number
[947699-46-9]
UNSPSC
12352005
Target
DNA Methyltransferase; Flavivirus; Virus Protease
Type
Reference compound
Related Pathways
Anti-infection; Epigenetics
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/zikv-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C1OCC=C1/C=C/[C@@H]2C(CC[C@]3([H])[C@@](COC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)(C)/C(CC[C@@]23C)=N/O)=C
Molecular Formula
C39H41NO4
Molecular Weight
587.75
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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