Antifungal agent 40
Antifungal agent 40 is an antifungal agent which extends into the narrow hydrophobic pocket II of C.alb. CYP51. Antifungal agent 40 has an inhibitory effect on lanosterol 14α-demethylase (CYP51) . Antifungal agent 40 inhibits biofilm formation[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antifungal-agent-40.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(C([Se]C(C2=CC=C(Cl)C=C2)CN3C=CN=C3)CN4C=CN=C4)C=C1
Molecular Formula
C22H20Cl2N4Se
Molecular Weight
490.29
References & Citations
[1]Hang Xu, et al. Discovery of novel selenium-containing azole derivatives as antifungal agents by exploiting the hydrophobic cleft of CYP51. Eur J Med Chem. 2022 Aug 28;243:114707.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PKSM040788 100 µg
Recombinant Mouse Dectin-1/CLEC7A Protein (His Tag)
Sign In for Pricing
View Details 
