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Antifungal agent 40

Antifungal agent 40 is an antifungal agent which extends into the narrow hydrophobic pocket II of C.alb. CYP51. Antifungal agent 40 has an inhibitory effect on lanosterol 14α-demethylase (CYP51) . Antifungal agent 40 inhibits biofilm formation[1].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352005

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antifungal-agent-40.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC=C(C([Se]C(C2=CC=C(Cl)C=C2)CN3C=CN=C3)CN4C=CN=C4)C=C1

Molecular Formula

C22H20Cl2N4Se

Molecular Weight

490.29

References & Citations

[1]Hang Xu, et al. Discovery of novel selenium-containing azole derivatives as antifungal agents by exploiting the hydrophobic cleft of CYP51. Eur J Med Chem. 2022 Aug 28;243:114707.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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